1. How to choose specific omics and datasets?


Step 1: Go to menu bar and chose specific omics and chose specific study of interest.

2. How to obtain differentially expressed genes?


Go to gene expression page of Mammonc-DB and consider left panel for analysis.







3. How to query for specific gene in a particular RNA-seq dataset?


Step 3: Go to gene expression page of Mammonc-DB and consider right panel for analysis.







Example

3a: How to explore expression profile of gene of interest based on clinico-pathologic factors?







Example of SEMA3B expression based on different clincial features in TCGA.

3b: How to obtain Kaplan meier plot from Mammonc-DB?







Example of XRCC4 survival analysis based on different clincial features available in TCGA.

4. How to query for specific gene in a particular scRNA-seq dataset?


Step 4: Go to gene expression page of Mammonc-DB and consider scRNA-seq button on top for analysis.




5. How to query for specific gene in a particular ChIP-seq dataset?


Step 5: Go to gene regulation page of Mammonc-DB and consider the panel for analysis.




Example of ER binding sites for RET in MCF7 breast cancer cell line.

6. How to query for specific protein in CPTAC dataset?


Step 6: Go to protein expression page of Mammonc-DB and consider the panel for analysis.




Example of TK1 expression and classifications associated.